Gait Verification using Knee Acceleration Signals

A novel gait recognition method for biometric applications is proposed. The approach has the following distinct features. First, gait patterns are determined via knee acceleration signals, circumventing difficulties associated with conventional vision-based gait recognition methods. Second, an automatic procedure to extract gait features from acceleration signals is developed that employs a multiple-template classification method. Consequently, the proposed approach can adjust the sensitivity and specificity of the gait recognition system with great flexibility. Experimental results from 35 subjects demonstrate the potential of the approach for successful recognition. By setting sensitivity to be 0.95 and 0.90, the resulting specificity ranges from 1 to 0.783 and 1.00 to 0.945, respectively

The Characteristics and Applications of Ceramic Laser Fusion and Ceramic Laser Sintering

The aim of present study is to investigate the possible application of the ceramic parts which are fabricated with the process of Ceramic Laser Fusion or Ceramic Laser Sintering. The experimental results reveal: (1) CLF can lead to a reduction in the porosity of the ceramic part but also can induce micro-cracks. Therefore, this process cannot produce a part with the required strength by a post-process of infiltration; (2) CLS is capable of fabricating a ceramic part with high porosity. By adjusting the slurry formulation and varying the scanning energy, the open porosity can be over 90vol% of the total porosity. After a post-process of infiltration, the density can be increased to 95%; therefore, CLS can apply to produce a part with high strength. Because the high open porosity leads to a good permeability, the process of CLS is suitable for the fabrication of ceramic shell mold.Mechanical Engineerin

Structure of the saxiphilin:saxitoxin (STX) complex reveals a convergent molecular recognition strategy for paralytic toxins.

Dinoflagelates and cyanobacteria produce saxitoxin (STX), a lethal bis-guanidinium neurotoxin causing paralytic shellfish poisoning. A number of metazoans have soluble STX-binding proteins that may prevent STX intoxication. However, their STX molecular recognition mechanisms remain unknown. Here, we present structures of saxiphilin (Sxph), a bullfrog high-affinity STX-binding protein, alone and bound to STX. The structures reveal a novel high-affinity STX-binding site built from a "proto-pocket" on a transferrin scaffold that also bears thyroglobulin domain protease inhibitor repeats. Comparison of Sxph and voltage-gated sodium channel STX-binding sites reveals a convergent toxin recognition strategy comprising a largely rigid binding site where acidic side chains and a cation-π interaction engage STX. These studies reveal molecular rules for STX recognition, outline how a toxin-binding site can be built on a naïve scaffold, and open a path to developing protein sensors for environmental STX monitoring and new biologics for STX intoxication mitigation

Plans for phase coherent long baseline interferometry for geophysical applications using the Anik-B communications satellite

A pilot project to establish an operational phase stable very long baseline interferometer (VLBI) for geophysical studies is described. Methods for implementation as well as practical applications are presented

Cognitive impairment and decline in cognitively normal older adults with high amyloid-β: A meta-analysis

AbstractIntroductionThis meta-analysis aimed to characterize the nature and magnitude of amyloid (Aβ)-related cognitive impairment and decline in cognitively normal (CN) older individuals.MethodMEDLINE Ovid was searched from 2012 to June 2016 for studies reporting relationships between cerebrospinal fluid or positron emission tomography (PET) Aβ levels and cognitive impairment (cross-sectional) and decline (longitudinal) in CN older adults. Neuropsychological data were classified into domains of episodic memory, executive function, working memory, processing speed, visuospatial function, semantic memory, and global cognition. Type of Aβ measure, how Aβ burden was analyzed, inclusion of control variables, and clinical criteria used to exclude participants, were considered as moderators. Random-effects models were used for analyses with effect sizes expressed as Cohen's d.ResultsA total of 38 studies met inclusion criteria contributing 30 cross-sectional (N = 5005) and 14 longitudinal (N = 2584) samples. Aβ-related cognitive impairment was observed for global cognition (d = 0.32), visuospatial function (d = 0.25), processing speed (d = 0.18), episodic memory, and executive function (both d's = 0.15), with decline observed for global cognition (d = 0.30), semantic memory (d = 0.28), visuospatial function (d = 0.25), and episodic memory (d = 0.24). Aβ-related impairment was moderated by age, amyloid measure, type of analysis, and inclusion of control variables and decline moderated by amyloid measure, type of analysis, inclusion of control variables, and exclusion criteria used.DiscussionCN older adults with high Aβ show a small general cognitive impairment and small to moderate decline in episodic memory, visuospatial function, semantic memory, and global cognition

Artifacts with uneven sampling of red noise

The vast majority of sampling systems operate in a standard way: at each tick of a fixed-frequency master clock a digitizer reads out a voltage that corresponds to the value of some physical quantity and translates it into a bit pattern that is either transmitted, stored, or processed right away. Thus signal sampling at evenly spaced time intervals is the rule: however this is not always the case, and uneven sampling is sometimes unavoidable. While periodic or quasi-periodic uneven sampling of a deterministic signal can reasonably be expected to produce artifacts, it is much less obvious that the same happens with noise: here I show that this is indeed the case only for long-memory noise processes, i.e., power-law noises $1/f^\alpha$ with $\alpha > 2$. The resulting artifacts are usually a nuisance although they can be eliminated with a proper processing of the signal samples, but they could also be turned to advantage and used to encode information.Comment: 5 figure

Long-term X-ray Variability of Ultraluminous X-ray Sources

Long-term X-ray modulations on timescales from tens to hundreds of days have been widely studied for X-ray binaries located in the Milky Way and the Magellanic Clouds. For other nearby galaxies, only the most luminous X-ray sources can be monitored with dedicated observations. We here present the first systematic study of long-term X-ray variability of four ultraluminous X-ray sources (ESO 243-49 HLX-1, Holmberg IX X-1, M81 X-6, and NGC 5408 X-1) monitored with Swift. By using various dynamic techniques to analyse their light curves, we find several interesting low-frequency quasi-periodicities. Although the periodic signals may not represent any stable orbital modulations, these detections reveal that such long-term regular patterns may be related to superorbital periods and structure of the accretion discs. In particular, we show that the outburst recurrence time of ESO 243-49 HLX-1 varies over time and suggest that it may not be the orbital period. Instead, it may be due to some kinds of precession, and the true binary period is expected to be much shorter.Comment: 15 pages, 8 figures; accepted for publication in MNRA